View Clinical Trial (Medical Research Study)
Behavioral and Neuroimaging Changes After Cognitive Rehab in TBI and MCI
| City: |
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Decatur |
| State: |
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Georgia |
| Zip Code: |
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30033 |
| Conditions: |
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Mild Cognitive Impairment - Alzheimer's Disease - Traumatic Brain Injury |
| Purpose: |
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Memory deficits are common after traumatic brain injuries (TBI) and are characteristic of
various forms of dementia, such as Alzheimer's disease and its common precursor mild
cognitive impairment (MCI). This project intends to assess the efficacy of cognitive
rehabilitation in these patient populations. We will also use neuroimaging (functional
magnetic resonance imaging - fMRI) to assess changes in brain activity that occur following
cognitive rehabilitation.
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| Study Summary: |
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| Criteria: |
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Inclusion Criteria:
General inclusion criteria (all patients):
- A minimum of 12 years of education or attainment of a Graduation Equivalency Diploma;
- All medications stable for approximately 3 months;
- No history of severe mental illness;
- No current untreated alcohol or substance abuse/dependence;
- English as native and preferred language;
- MRI-compatible if taking part in fMRI studies 7) Able to give informed consent.
MCI Inclusion Criteria:
- Diagnosis of amnestic MCI based on criteria set forth by Petersen (2004).
Additionally, other potential causes of cognitive deficit ruled out by the referring
physician;
- 55 years of age or older.
TBI Inclusion criteria:
- History of a mild to moderate TBI;
- No history of other neurological disease or injury;
- A minimum of 6 months and maximum of 5 years post-onset of TBI;
- 18 - 45 years old.
Exclusion Criteria:
- History of neurological disease or injury (other than TBI)
- History of severe mental illness
- Current untreated alcohol or substance abuse
- Other conditions may exclude; please discuss with contact
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| NCT ID: |
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NCT00714571 |
| Primary Contact: |
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Principal Investigator
Benjamin M. Hampstead, PhD
Atlanta VA Medical and Rehab Center, Decatur
Justin F Hartley, BA
Phone: (404) 712-0936
Email: jhartl3@emory.edu
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| Backup Contact: |
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Email: mmgilli@emory.edu
Mary M Gillis, MA
Phone: (404) 712-9205
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| Location Contact: |
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Decatur, Georgia 30033
United States
Justin F Hartley, BA
Phone: 404-712-0936
Email: jhartl3@emory.edu
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 22, 2013 |
| Modifications to this listing: |
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