A Phase I Safety and Tolerability Study of Vorinostat in Combination With Sorafenib in Patients With Advanced Solid Tumors, With Exploration of Two Tumor-Type Specific Expanded Cohorts at the Recommended Phase 2 Dose (Renal Cell Carcinoma and Non-Small Ce
| City: |
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Aurora |
| State: |
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Colorado |
| Zip Code: |
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80045 |
| Conditions: |
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Advanced Solid Tumors |
| Purpose: |
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The main purpose of this study is to:
- Evaluate the safety of vorinostat in combination with sorafenib.
- Determine the largest dose of vorinostat + sorafenib that can be given safely to
humans.
- Determine if vorinostat + sorafenib are effective in stopping tumors from growing or in
decreasing their size.
- Study the side effects of vorinostat + sorafenib.
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| Study Summary: |
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| Criteria: |
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Eligibility criteria include but are not limited to:
- 18 years or older with advanced solid tumor(s),
- Renal cell or non-small cell lung cancer.
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| NCT ID: |
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NCT00635791 |
| Primary Contact: |
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Principal Investigator
David R Camidge, MD
University of Colorado, Denver
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| Backup Contact: |
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N/A |
| Location Contact: |
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Aurora, Colorado 80045
United States
Stacy Grolnic
Phone: 720-848-0655
Email: stacy.grolnic@ucdenver.edu
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 19, 2013 |
| Modifications to this listing: |
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