Monitoring Targeted Lung Cancer Treatments With FDG-PET/CT
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| City: |
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Los Angeles |
| State: |
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California |
| Zip Code: |
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90095 |
| Conditions: |
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Lung Cancer |
| Purpose: |
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RATIONALE: Measuring changes in glucose metabolism in patients with cancer may help doctors
predict how patients respond to treatment.
PURPOSE: This clinical trial is studying glucose metabolism in patients with non-small cell
lung cancer treated with targeted therapy and chemotherapy.
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| Study Summary: |
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OBJECTIVES:
- Determine the prognostic significance of changes in glucose metabolism measured by
fludeoxyglucose F 18 positron emission tomography (FDG-PET)/CT scan in patients with
non-small cell lung cancer treated with targeted drugs comprising gefitinib, erlotinib
hydrochloride, or other ErbB inhibitors, cyclooxygenase-2 inhibitors, or estrogen
receptor blockers in combination with conventional chemotherapy.
OUTLINE: This is a prospective study.
Patients undergo fludeoxyglucose F 18 positron emission tomography (FDG-PET) scan and CT
scan at baseline and at 2 weeks and 12 weeks after receiving targeted anticancer treatment.
Metabolic changes detected by FDG-PET and size changes identified by CT scan are related to
patient outcome and tumor response to treatment.
PROJECTED ACCRUAL: A total of 120 patients will be accrued for this study.
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| Criteria: |
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Inclusion Criteria:
- Histologically or cytologically confirmed non-small cell lung cancer
- Any disease stage allowed
- Undergoing targeted treatment
Exclusion Criteria:
None
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| NCT ID: |
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NCT00450567 |
| Primary Contact: |
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Study Chair
Johannes Czernin, MD
Jonsson Comprehensive Cancer Center
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| Backup Contact: |
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N/A |
| Location Contact: |
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Los Angeles, California 90095
United States
There is no listed contact information for this specific location.
Site Status: N/A |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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June 19, 2013 |
| Modifications to this listing: |
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