View Clinical Trial (Medical Research Study)
NYU Lung Cancer Biomarker Center
| City: |
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New York |
| State: |
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New York |
| Zip Code: |
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10016 |
| Conditions: |
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Lung Cancer |
| Purpose: |
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RATIONALE: Screening tests that use biomarkers may help doctors find tumor cells early and
plan effective treatment for lung cancer.
PURPOSE: This clinical trial is studying biomarkers in screening participants for lung
cancer.
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| Study Summary: |
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OBJECTIVES:
- Identify and validate biomarkers for the early detection of lung cancer in individuals
at low- or high-risk for smoking-related cancers.
- Identify preneoplastic cellular changes and lesions in these patients.
OUTLINE: Participants are stratified according to lung cancer risk status (with or without
increased risk).
Group 1 (screening cohort): Participants complete a questionnaire and undergo pulmonary
function testing, multidetector chest CT scan, sputum induction, and phlebotomy.
Group 2 (rule-out lung cancer): Participants complete the same questionnaire and undergo the
same tests and scans as in group 1. Some participants may undergo fiberoptic bronchoscopy
based upon CT scan results with transbronchial or endobronchial biopsies. Some participants
may undergo lung resection. Tissue samples are collected from surgery or biopsy.
PROJECTED ACCRUAL: A total of participants will be accrued for this study.
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| Criteria: |
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DISEASE CHARACTERISTICS:
- Screening Cohort
- At high- or low-risk for lung cancer
- Smoking history ≥ 20 pack years*
- With or without workplace exposure to asbestos
- NOTE: * Participants with < 20 pack years of smoking are eligible if 50 years of age
or older
- Rule-Out Lung cancer group
- Referred for evaluation of suspicious nodules with 1 of the following diagnoses:
- Lung cancer
- Nonmalignant nodules (control group)
PATIENT CHARACTERISTICS:
- Not pregnant
- No prior malignancy except nonmelanoma skin cancer
PRIOR CONCURRENT THERAPY:
- Not specified
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| NCT ID: |
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NCT00301119 |
| Primary Contact: |
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Principal Investigator
William N. Rom, MD, MPH
New York University School of Medicine
William N Rom, MD, MPH
Phone: 212-263-6479
Email: william.rom@nyumc.org
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| Backup Contact: |
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Email: ellen.eylers@nyumc.org
Ellen M Eylers, RN, MSN, MPH
Phone: 212-263-6126
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| Location Contact: |
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New York, New York 10016
United States
William N. Rom, MD, MPH
Phone: 212-263-6479
Email: william.rom@med.nyu.edu
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 17, 2013 |
| Modifications to this listing: |
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